DelveInsight’s ‘TIM-3-Next Generation Immunotherapy—Competitive Landscape and Market Forecast–2035’ report delivers an in-depth understanding of the TIM-3 as well as the market trends of TIM-3-Next Generation Immunotherapy in the United States, EU5 (Germany, Spain, Italy, France, and the United Kingdom), and Japan.
Key Highlights of the TIM-3-Next Generation Immunotherapy Market
The Key Companies working in the TIM-3-Next Generation Immunotherapy market include GlaxoSmithKline, Novartis, Bristol-Myers Squibb, Ono Pharmaceuticals BeiGene, Incyte Biosciences/Agenus, Symphogen, Roche, Eli Lilly, Symphogen and many others
The Key Therapies working in the TIM-3-Next Generation Immunotherapy market include Sym023, TSR-022, MBG453, ONO-7807, BMS-986258 and many others
TIM-3-Next Generation Immunotherapy Overview
Cancer immunotherapy (CI) is rapidly advancing and can now be considered to be the “fifth pillar” of cancer therapy, joining the ranks of surgery, cytotoxic chemotherapy, radiation, and targeted therapy. The CI that has sparked the most interest involves antibodies to inhibitory immune checkpoint molecules. Fighting cancer with immunotherapy has revolutionized treatment for some patients and therapies targeting the immune checkpoint molecules such as CTLA-4 and PD-1 have achieved durable responses in melanoma, renal cancer, Hodgkin’s disease, and lung cancer. However, the success rate of these treatments has been low and a large number of cancers, including colorectal cancer remain largely refractory to CTLA-4 and PD-1 blockade.
TIM-3 is a co-inhibitory receptor that is expressed on IFN-γ-producing T cells, FoxP3+ Treg cells, and innate immune cells (macrophages and dendritic cells) where it has been shown to suppress their responses upon interaction with their ligand(s). TIM-3 has gained prominence as a potential candidate for cancer immunotherapy, where it has been shown that in vivo blockade of TIM-3 with other checkpoint inhibitors enhances anti-tumor immunity and suppresses tumor growth in several preclinical tumor models.
TIM-3-Next Generation Immunotherapy Epidemiology Insights
The prevalence of TIM-3-Next Generation Immunotherapy increases with age. In 2005-2008 an estimated 33.5% of U.S. adults older than 20 years of age had high LDL-C levels. Of these individuals with elevated LDL-C levels, only 48.1% received treatment, and 33.2% had their LDL-C controlled. The prevalence of LDL-C control seemed to be the lowest amongst individuals who were uninsured, Mexican American, or had income below the poverty level.
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The Report Covers the TIM-3-Next Generation Immunotherapy Epidemiology Segmented by:
TIM-3-Next Generation Immunotherapy diagnosed cases
Total TIM-3-Next Generation Immunotherapy incident cases
Total TIM-3-Next Generation Immunotherapy prevalent cases
TIM-3-Next Generation Immunotherapy Treatment cases
TIM-3-Next Generation Immunotherapy Market Outlook
The TIM-3-Next Generation Immunotherapy market outlook of the report helps to build a detailed comprehension of the historic, current, and forecasted TIM-3-Next Generation Immunotherapy market trends by analyzing the impact of current TIM-3-Next Generation Immunotherapy therapies on the market, unmet needs, drivers and barriers, and demand for better technology.
This segment gives a thorough detail of the TIM-3-Next Generation Immunotherapy market trend of each marketed drug and late-stage pipeline therapy by evaluating their impact based on the annual cost of therapy, inclusion and exclusion criteria, mechanism of action, compliance rate, growing need of the market, increasing patient pool, covered patient segment, expected launch year, competition with other therapies, brand value, their impact on the market and view of the key opinion leaders. The calculated TIM-3-Next Generation Immunotherapy market data are presented with relevant tables and graphs to give a clear view of the market at first sight.
According to DelveInsight, the TIM-3-Next Generation Immunotherapy market in 7MM is expected to witness a major change in the study period 2019-2032.
Key Companies Working in the TIM-3-Next Generation Immunotherapy Market
• Novartis
• Bristol-Myers Squibb/ Ono Pharmaceuticals
• BeiGene
• Incyte Biosciences/Agenus
• Symphogen
• Roche
• Eli Lilly
And many others
TIM-3-Next Generation Immunotherapy Therapies Covered and Analyzed in the Report
Sym023
TSR-022
MBG453
Learn more about the Key Companies and Emerging Therapies in the TIM-3-Next Generation Immunotherapy Market
Table of Contents
Key Insights
TIM-3-Next Generation Immunotherapy Introduction
Executive Summary of TIM-3-Next Generation Immunotherapy
Disease Background and Overview
Epidemiology and Patient Population
TIM-3-Next Generation Immunotherapy Emerging Therapies
Market Access and Reimbursement of Therapies
Market Drivers
Market Barriers
Appendix
Report Methodology
DelveInsight Capabilities
Disclaimer
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